Gaël Monfils (52) → replaced by 
Nuno Borges (99)
Kamil Majchrzak (77) → replaced by 
Vasek Pospisil (100)
Reilly Opelka (38) → replaced by 
Zhang Zhizhen (101)
Carlos Alcaraz (1) → replaced by 
Attila Balázs (101 PR)
Simona Halep (10) → replaced by 
Varvara Gracheva (94)-
Daria Saville (54) → replaced by 
Ysaline Bonaventure (95) - & Wang Qiang (91) → replaced by
Harriet Dart (96) - & Sara Sorribes Tormo (62) → replaced by
Kateryna Baindl (98) - &
Naomi Osaka (42) → replaced by Dayana Yastremska (99)
The following player would have been seeded, but withdrew before the tournament began.
| Rank | Player | Points before | Points defending | Points after | Withdrawal reason |
|---|---|---|---|---|---|
| Simona Halep |
2,381 | 240 | 2,141 | Provisional suspension due to positive doping test |
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